我所生化代谢的研究发现氟乙酸钠有显著的杀日本血吸虫的作用,作者等据此合成了125个氟乙酰胺类化合物。动物实验治疗结果证明,122个化合物有抗血吸虫作用,其中21个化合物的减虫率达90～100％,而毒性较之氟乙酸大幅度地降低,有些化合物剂量可高达5～10mg/鼠,但离进行临床试验还有一定的差距。 My biochemical metabolism study found that sodium fluoride has a significant role in killing Schistosoma japonicum, the authors accordingly synthesized 125 fluoroacetamide compounds. The results of animal experiments show that 122 compounds have anti-schistosome activity, of which 21 compounds have an eradication rate of 90-100%, while their toxicity is significantly reduced compared to fluoroacetic acid. Some compounds can be administered in doses of up to 5-10 mg / mouse, However, there is a certain gap between the clinical trials.