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观察不同时间的ＯＪ病人血浆ＥＴ、ＡＮＰ含量及其与肝、肾、心、肺等多脏器功能指标的关系，结果在ＯＪ病人血浆中ＥＴ、ＡＮＰ含量增加，且与多脏器功能损害密切相关。提示ＥＴ、ＡＮＰ可以作为ＯＪ病情及其脏器功能的判断指标；ＥＴ在ＯＪ并发症中有明显的发病作用，而ＡＮＰ作为ＥＴ的拮抗物在ＯＪ引起的多脏器功能失常综合征中可能具有保护作用。
The levels of plasma ET and ANP in patients with OJ at different time points and their relationship with the function indexes of multiple organs such as liver, kidney, heart and lung were observed. The results showed that the content of ET and ANP in the plasma of OJ patients was increased and the function of multiple organs was impaired Related. Suggesting that ET and ANP can be used as indicators of OJ disease and its organ function; ET has a significant role in the pathogenesis of OJ, and ANP as an antagonist of ET may have in OJ-induced multiple organ dysfunction syndrome Protective effects.