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百分浓度是药物浓度的主要表示方法,分为三种:(1)重量/重量百分浓度,(2)重量/体积百分浓度,(3)体积/体积百分浓度。软膏制剂中的浓度主要以重量百分浓度来表示(即每100 g软膏中含主药多少g,其浓度便是百分之几)。某些文章中使用重量百分浓度的概念不当,因而出现错误,现举例如下: 1.15%尿素乳膏[徐中立:药学通报(7):311,1979] 尿素150g,单硬脂酸甘油酯100g,白凡士林50 g.地蜡100g,液体石蜡500g,司盘-40(或司盘-60)2.5g、乳化剂OP5 g,尼泊金乙酯1 g、BHT0.15~0.25 g.蒸馏水250ml。该处方中制剂总重量约为1150 g、尿素150g,百分
Percent concentration is the main method of drug concentration, divided into three types: (1) weight / weight percent, (2) weight / volume percent concentration, (3) volume / volume percent concentration. The concentration in the ointment preparation is expressed mainly in weight percent (ie, how many grams of primary drug is contained per 100 g of ointment, at a concentration of a few percent). Some articles using the concept of weight percent concentration of improper, and thus an error, for example as follows: 1.15% urea cream [Xu Zhongli: Pharmacology Bulletin (7): 311,1979] urea 150g, 100g glyceryl monostearate , White petrolatum 50 g, ozocerite 100 g, liquid paraffin 500 g, Span-40 (or Span-60) 2.5 g, emulsifier OP 5 g, ethyl paraben 1 g, BHT 0.15 ~ 0.25 g Distilled water 250 ml . The formulation of the total weight of about 1150 g, urea 150g, percent