自1980年以来,大量新型高效的头孢菌素(即氨噻肟头孢,氧哌羟苯唑头孢和氨噻三嗪头孢)已开始应用于临床。尽管它们具有高效,抗菌谱广的优点,但对某些假单胞菌和葡萄球菌效能较低,甚至无效。这里报导的一种新型头孢菌素:3—[2,3—环戊基—1—吡啶盐)—甲基]—7—[2—顺式—甲氧亚胺基—2—(2—氨基噻唑基—4—基)—乙酰胺基)—头孢—3—内—4—羧酸盐(HR810~*),对临床上所有的菌,包括假 Since 1980, a large number of new and highly effective cephalosporins (ie, cefotaxime, methotrexate cefadroxil and cefotaxime) have begun to be used clinically. Although they have the advantages of high efficiency and broad antibacterial spectrum, they are less effective or even ineffective against certain Pseudomonas and Staphylococci. A new type of cephalosporin reported here is 3- [2,3-cyclopentyl-1-pyridinium) -methyl] -7- [2-cis-methoxyimino-2- Amino-thiazolyl-4-yl) -acetamido) -cemid-3-endo-4-carboxylate (HR 810 ~ *)