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对结直肠癌患者的一级亲属(FDRs)推荐行结肠镜检查进行筛检,现只有少数前瞻性对照研究评价了结肠镜检查在人群中的筛检效果。为了评价FDRs人群中结直肠肿瘤(腺瘤和腺癌)的患病率与一般人群的差别,并探索可能使FDRs患病风险增加的因素,Armelao F等采用横向研究的方法,对1 252位年龄为45～75岁的直肠癌患者的FDRs和765位一般人群行结
Colonoscopy is recommended for first-degree relatives (FDRs) of patients with colorectal cancer and screening studies are now available in only a small number of prospective, controlled studies evaluating colonoscopy in the population. In order to assess the difference between the prevalence of colorectal tumors (adenoma and adenocarcinoma) and the general population in FDRs and to explore the factors that may increase the risk of FDRs, Armelao F et al. FDRs in patients with rectal cancer aged 45-75 years old and 765 people in the general population