论文部分内容阅读
本实验用免疫组织化学ＡＢＣ法发现大鼠胼胝体内存在生长抑素免疫反应阳性轴突．此阳性轴突可见于生后不同发育阶段及成年大鼠的胼胝体内．出生时胼胝体内此轴突的数量很少；生后１周内其密度逐渐增高，至第２周初期达到高峰，此时胼胝体内可见大量生长抑素阳性轴突．然而，至第２周末，生长抑素阳性胶胝体轴突的密度已下降至接近成年时的水平，即仅有少量此纤维存在于胼胝体内。这些结果提示在大鼠早期生后发育过程中许多生长抑素阳性胼胝体轴突是暂时性的．结合本文作者等以往对成年和发育中大鼠和猫的与胼胝体联系的神经介质的研究结果，可以认为胼胝体中的活性物质是多样的，在哺乳动物大脑皮质发育中可能起着不同的作用。
In this study, immunohistochemical ABC method was used to detect the presence of somatostatin-immunoreactive axons in the corpus callosum of rats. This positive axon can be found in different developmental stages of postnatal and adult calluses of the body. At birth, the number of axons in the corpus callosum is small; the density gradually increases within 1 week after birth and reaches a peak at the beginning of the second week. At this time, a large number of somatostatin-positive axons can be seen in the corpus callosum. However, by the second weekend, the density of somatostatin-positive Colloidal axons had dropped to nearly adult levels, ie only a small amount of this fiber was present in the corpus callosum. These results suggest that many somatostatin-positive corpus callosum axons are transient during the early postnatal development in rats. In the past, the authors of the present study showed that the active substances in the corpus callosum are diverse and may play different roles in mammalian cerebral cortical development as a result of previous studies on the neurotransmitter associated with the corpus callosum in adult and developing rats and cats.