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本文对不同剂量X射线照射雄性小鼠后诱发的多价体的遗传危险度作了评价。低刺量率0.05Gy/min小于1.00Gy X射线照射减数分裂前期精母细胞、精原细胞及精原干细胞后,多价体发生率均随剂量升高而增加,预期平衡易位配子发生率平均分别为1.22×10~(-5)、1.68×10~(-5)、4.02×10~(-5)/配子·10mGy,其倍加剂量分别约为0.05、0.036、0.015Gy。较大剂量率(0.28Gy/min)较大剂量(1.00～4.00Gy)X射线照射精原干细胞后,多价体也随剂量增加而增多,预期平衡易位配子发生率为1.65×10~(-5)/配子·10mGy,倍加剂量约为0.036Gy。预期自发平衡易位配子发生率为6.0×10~(-5)/配子。
In this paper, we evaluated the genetic risk of polyvalence induced by different doses of X-ray in male mice. Low-dose rate of 0.05Gy / min less than 1.00Gy X-ray irradiation pre-meiotic pre-spermatocytes, spermatogonia and spermatogonial stem cells, the incidence of polyvalent increases with increasing doses expected to balance the occurrence of translocated gamete The average rates were 1.22 × 10 -5, 1.68 × 10 -5, 4.02 × 10 -5 / gamete · 10 mGy, respectively. The doubling doses were about 0.05, 0.036 and 0.015 Gy, respectively. After the larger dose (0.28 Gy / min) and the higher dose (1.00-4.00 Gy) of x-rays irradiated spermatogonial stem cells, the multivalent body also increased with the increase of dose. The incidence of balanced transposon was expected to be 1.65 × 10 ~ -5) / gamete · 10mGy, double dosage is about 0.036Gy. The incidence of spontaneous equilibrium translocation is expected to be 6.0 × 10 -5 / gameto.