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目的观察消旋卡多曲颗粒联合蒙脱石散治疗婴幼儿轮状病毒肠炎的临床疗效。方法 2009年3月~2010年3月,120例轮状病毒肠炎患儿随机分为两组,观察组60例给予消旋卡多曲颗粒联合蒙脱石散治疗,对照组60例仅采用蒙脱石散治疗,对比观察两组的临床疗效以临床指标的变化。结果观察组的总有效率为86.7%,明显高于对照组的71.7%(P﹤0.05);并且,观察组的止吐时间、脱水纠正时间、大便次数正常时间和大便性状正常时间均明显短于对照组(P﹤0.05)。结论消旋卡多曲颗粒联合蒙脱石散对婴幼儿轮状病毒肠炎进行治疗,能够明显提高临床疗效,安全性高,值得临床推广应用。
Objective To observe the clinical efficacy of racecadotril granules combined with montmorillonite in the treatment of infantile rotavirus enteritis. Methods From March 2009 to March 2010, 120 children with rotavirus enteritis were randomly divided into two groups. 60 cases in the observation group were treated with racecadotril granules combined with montmorillonite powder, and 60 cases in the control group were only treated with Mongolian Triptolide treatment, comparative observation of clinical efficacy of the two groups with changes in clinical indicators. Results The total effective rate of the observation group was 86.7%, which was significantly higher than that of the control group (71.7%, P <0.05). And the antiemetic time, dehydration correction time, normal stool frequency and stool normal time in observation group were significantly shorter In the control group (P <0.05). Conclusion The combination of racemic cardiotonic granules and montmorillonite powder for the treatment of infantile rotavirus enteritis can significantly improve the clinical efficacy and safety, which is worthy of clinical application.