肝豆状核变性(Wilson病)是一种常染色体隐性遗传的铜代谢障碍的疾病,主要以肢体震颤、肝功能损害、铜代谢异常及角膜色素环(K-F环)为特征。我们曾遇1例,报告如下。男性,23岁。患者因间歇性头痛、鼻衄年余,四肢震颤、流涎、步态不稳2个月,于1982年11月6日入院。家族史无特殊。体检:神志清,答话口齿不清。巩膜无黄染。肝脾(-)。双眼瞳孔等大,对光反射存在,眼底(-)。咽反射迟钝,伸舌不灵活。四肢肌张力稍增强,双手呈不自主震颤,指鼻试验恢 Wilson’s disease (Wilson’s disease) is an autosomal recessive disorder of copper metabolism that is characterized by limb tremor, impaired liver function, abnormal copper metabolism, and the corneal pigment ring (K-F loop). We have encountered a case, the report is as follows. Male, 23 years old. Patients due to intermittent headache, epistaxis more than a year, limb tremor, drooling, unsteady gait 2 months, on November 6, 1982 admission. No special family history. Physical examination: Consciousness, answer slurred speech. Sclera without yellow dye. Liver and spleen (-). Pupil and other large eyes, the presence of light reflex, fundus (-). Slow pharyngeal reflex, extensor tongue is not flexible. Limb muscle tension increased slightly, his hands were involuntary tremor, finger nasal test restored