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目的:探讨西帕依固龈液联合西吡氯铵治疗牙龈炎的临床疗效。方法:选择我院于2013年10月-2015年2月收治的130例牙龈炎患者,将其随机分成实验组和对照组各65例,对照组给予西吡氯铵治疗,实验组给予西帕依固龈液联合西吡氯铵治疗,比较两组患者的菌斑指数(PLI)、牙龈指数(GI)、龈沟出血指数(SBI)以及治疗疗效。结果:治疗8天后,实验组和对照组患者的治疗总有效率分别为96.92%和81.54%,组间比较差异具有统计学意义(P<0.05)。两组患者治疗前PLI、GI、SBI比较无显著差异(P>0.05);治疗后,两组患者各项指标均较治疗前有所改善,与各自治疗前比较差异具有统计学意义(P<0.05),但两组治疗后的指标差异无统计学意义(P>0.05)。两组患者不良反应的发生率分别为10.77%和9.23%,差异无统计学意义(x~2=0.0855,P>0.05)。结论:西帕依固龈液与西吡氯铵联合使用治疗牙龈炎具有确切的疗效,同时具有较高的安全性。
Objective: To investigate the clinical efficacy of Xipayi gingival fluid combined with cetylpyridinium chloride in the treatment of gingivitis. Methods: A total of 130 gingivitis patients who were admitted to our hospital from October 2013 to February 2015 were randomly divided into experimental group (65 cases) and control group (65 cases), control group (treated with cetylpyridinium chloride) and experimental group Gingival crevicular fluid combined with cetylpyridinium chloride treatment, plaque index (PLI), gingival index (GI), sulcus bleeding index (SBI) and treatment efficacy were compared between the two groups. Results: After 8 days of treatment, the total effective rates of the experimental group and the control group were 96.92% and 81.54%, respectively. The difference between the two groups was statistically significant (P <0.05). There was no significant difference in PLI, GI and SBI between the two groups before treatment (P> 0.05). After treatment, the indexes in both groups improved compared with those before treatment, with statistical significance (P < 0.05), but there was no significant difference between the two groups after treatment (P> 0.05). The incidence of adverse reactions in both groups were 10.77% and 9.23%, respectively, with no significant difference (x ~ 2 = 0.0855, P> 0.05). CONCLUSIONS: The combination of Xipayi gingival solution with cetylpyridinium for the treatment of gingivitis has definite curative effect and high safety.