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AIM: To investigate the adverse action of Helicobacter pylori(HP) (NCTC11637 strain ) and the therapeutic effect ofGypenosides (GP) isolated from Gynostemma pentaphyllum onulcer healing in rats. METHODS: After ulcer induction byacetic acid in the stomach, rats were divided into 4 groups. Theywere eithe given ig with distilled water or with CagA (+) andVacA (+) NCTC1163HP (1 mg·kg~(-1)·d~(-1) ) alone or togetherwith GP (15 or 45 mg·kg~(-1)·d~(-1) ) for 9 d. The changes of
METHODS: After investigate the adverse action of Helicobacter pylori (HP) (NCTC11637 strain) and the therapeutic effect of Glyososides (GP) isolated from Gynostemma pentaphyllum onulcer in rats. METHODS: After ulcer induction by acetic acid in the stomach, rats were divided into 4 groups. Theywere eithe given ig with distilled water or with CagA (+) and VacA (+) NCTC1163HP (1 mg · kg -1 · d -1) alone or togetherwith GP (15 or 45 mg · kg ~ (-1) · d ~ (-1)) for 9 d. The changes of