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To study the immunomodulatory effects of dihydreetorphine (DHE), the most powerful nacrotic analgesic synthesized up to now, the present studies systematically investigated its actions on immune functions in sub-chronically administered mice,72 h computer-controlled automatic intravenous injection rats,and intravenous self-administration rats.DHE significantly lowered the increase of body weight, decreased spleen and thymus weights, weakened the delayed-type hypersensitivity, reduced the
To study the immunomodulatory effects of dihydreetorphine (DHE), the most powerful nacrotic analgesic synthesized up to now, the present studies systematically investigating their actions on immune functions in sub-chronically administered mice, 72 h computer-controlled automatic intravenous injection rats, and intravenous self-administration rats. DDH significantly lowered the increase of body weight, decreased spleen and thymus weights, weakened the delayed-type hypersensitivity, reduced the