伯氨喹为根治间日疟及卵形疟唯一有效的抗疟药。间日疟原虫对伯氨喹的低敏感性,50年代在西太区和东南亚已有记载。在这些地区,经过一个正规疗程的治疗,复发率高达30％。最近在中南美洲也有报道,但低敏感性虫株的准确比例尚未确定。 本文报道一例用伯氨喹治疗间日疟失败 Primaquine is the only effective antimalarial for eradicating vivax malaria and ovale. The low sensitivity of Plasmodium vivax to primaquine was documented in the Western Pacific and Southeast Asia in the 1950s. In these areas, after a regular course of treatment, the recurrence rate as high as 30%. Recently, it has also been reported in Central and South America, but the exact proportion of low-sensitivity strains has not yet been determined. This article reports the failure of primaquine for the treatment of P. vivax in a patient