立体定向神经外科手术治疗帕金森病(PD)历史悠久,即通过在丘脑或丘脑下核制造损害灶以控制震颤、强直和运动不能。此术的靶点主要是丘脑腹前核、腹后核、中腹核(Vim)或未定区。其中Vim被证明对治疗震颤更为有效,在此核内制造小的毁损灶亦能获得满意疗效。目前多数作者均喜欢以Vim作为PD治疗的靶点,并倾向于用Vim刺激术替代Vim——丘脑切开术治疗此类疾病,本文作者报道33例次成功的经验。 Stereotactic neurosurgery for the treatment of Parkinson’s disease (PD) has a long history of impotence, rigidity and motor failure by creating focal lesions in the thalamic or subthalamic nuclei. The main target of this operation is the thalamic nucleus, ventral nucleus, Vim or undetermined region. Among them, Vim proved to be more effective in treating tremor and achieving satisfactory results in manufacturing small lesions in this nucleus. At present, most authors like to use Vim as the target of PD treatment and tend to use Vim stimulation instead of Vim - thalamic incision to treat such diseases. The authors reported 33 successful cases.