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目的 :调查分析本地区婴幼儿接种乙肝疫苗的效果。方法 :对本地区43家托幼机构的526名婴幼儿接种乙肝疫苗的情况进行回顾性研究。调查这526名婴幼儿执行乙肝疫苗免疫计划的情况,并检测其乙肝五项定量,比较其乙肝表面抗体阳性率。结果 :所有婴幼儿均完成了乙肝免疫计划,其中1~2岁婴幼儿的乙肝表面抗体阳性率为81.90%;2~4岁婴幼儿的乙肝表面抗体阳性率为68.05%;4~6岁幼儿的乙肝表面抗体阳性率72.29%。这526名婴幼儿乙肝表面抗体的平均阳性率为71.48%。其中2~4岁婴幼儿的乙肝表面抗体阳性率明显低于526名婴幼儿乙肝表面抗体的平均阳性率,二者相比差异显著,有统计学意义(P<0.05)。结论 :在婴幼儿出生后,应及时为其接种乙肝疫苗,并定期检查其乙肝表面抗体的含量,当其乙肝表面抗原含量HBsAg>10 IU/L时,应复种乙肝疫苗,保持其抗体的持续性。
Objective: To investigate the effect of hepatitis B vaccine in infants and young children in this area. Methods: A retrospective study was conducted on 526 infants who were vaccinated against hepatitis B in 43 nurseries in the area. Investigate 526 infants and young children to implement the hepatitis B vaccine immunization program, and test its five quantitative hepatitis B, HBsAg positive rate compared. Results: The hepatitis B immunization program was completed in all infants and young children. The positive rate of HBsAg in infants aged 1-2 years was 81.90%. The positive rate of HBsAg in infants 2-4 years old was 68.05% The positive rate of HBsAg was 72.29%. The average positive rate of HBsAg in 526 infants and young children was 71.48%. The positive rate of HBsAg in infants aged 2 ~ 4 years was significantly lower than that of 526 infants with HBsAg. There was significant difference between the two (P <0.05). Conclusions: After infants and young children are born, they should be given hepatitis B vaccine in time and their HBsAg should be checked regularly. When their HBsAg> 10 IU / L, hepatitis B vaccine should be used repeatedly to keep their antibodies sustained Sex.