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溃疡性结肠炎的病因不明,治疗方法仍依赖经验.本文报告37例强的松龙动脉内注射的治疗结果,并指出疗效与选择性肠系膜动脉造影所见之间的关系.患者年龄为15～58岁,平均30岁;男20例,女17例.病程平均4.5年(1个月至22年).所有病例均施行选择性肠系膜上、下动脉造影以及强的松龙选择性动脉内滴注.其中9例行数次动脉内滴注,以每次滴注作为1例评定疗效.在全部54次滴注中,4例病变在直肠或/和乙状结肠,15例在左半结肠,35例在全结肠,包括中毒性巨结肠5例.分别在肠系膜上、下动脉内手推注射强的松龙20～30mg,约30分钟内注完(1.5～2mg/min).治疗后2周观察疗效.
The etiology of ulcerative colitis is unknown, the treatment method is still dependent on experience.This article reports the results of 37 cases of prednisolone intra-arterial injections and points out the relationship between efficacy and selective mesenteric artery angiography.Patients aged 15 ~ 58 years old with an average of 30 years old, 20 males and 17 females with an average duration of 4.5 years (ranged from 1 month to 22 years) .All patients underwent selective superior mesenteric artery angiography and prednisolone selective arterial infusion Note: Nine of these patients underwent several intra-arterial instillations, with each instillation as a measure of efficacy. Of the 54 injections, 4 had lesions in the rectum or / and sigmoid colon, 15 in the left colon, 35 Cases in the whole colon, including toxic megacolon in 5 cases, respectively, in the superior mesenteric artery, intramuscular injection of prednisolone 20 ~ 30mg, about 30 minutes note (1.5 ~ 2mg / min) after 2 weeks Observe the effect.