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慢性肾脏疾病(CKD)患者抵抗力低,容易合并各种感染。三代头孢菌素类抗生素对CKD患者相对安全,成为临床医生的首选。然而,由于患者肾脏功能不同程度的损伤对药物代谢的影响,导致部分患者出现抗生素脑病。回顾我院2005-05-2009-11收治的9例CKD并发抗生素脑病的患者,现报告如下。1
Chronic kidney disease (CKD) patients with low resistance, easy to combine a variety of infections. Third-generation cephalosporin antibiotics are relatively safe for patients with CKD, becoming the clinician of choice. However, some patients have antibiotic encephalopathy due to the influence of varying degrees of damage on the renal function of the patient on the metabolism of the drug. Review of our hospital from 2005-05-2009-11 admitted to 9 cases of CKD patients with concurrent antibiotic encephalopathy, are as follows. 1