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本文对琼玉膏在通便作用方面进行了药理研究,结果表明:琼玉膏2.5g/kg及109g/kg对燥结失水型便秘小鼠的排便功能有促进作用,能使排便粒数增加(P<0.01);琼玉膏上述二剂量对燥结失水型便秘小鼠的肠管含水量有增加作用,能使小肠湿重、小肠含水量、大肠湿重、大肠含水量明显增加(P<0.05~0.01);琼玉膏对正常小鼠小肠推进功能无明显影响,但当小鼠小肠推进功能为阿托品的作用而出现缓慢时,琼玉膏则对小肠推进功能有促进作用。结果提示,琼玉膏对燥热或阴虚燥结便秘者,有一定的润肠通便作用。
In this article, the pharmacological study of Qiong Yu Ointment on the defecation effect was carried out. The results showed that: Qiong Yu Ointment 2.5g/kg and 109g/kg can promote the defecation function of dry dehydration constipation mice, and can make the defecation The number increased (P<0.01); Qiong Yu Ointment above two doses increased the bowel water content of mice with dry dehydration constipation, and could make the small intestine wet weight, small intestine water content, large intestine wet weight, large intestine water content. Significantly increased (P<0.05-0.01); Qiong Yu Ointment had no significant effect on the function of small intestine advancing in normal mice, but when the small intestine advancing function of mice was slow due to the effect of atropine, Qiong Yu ointment was applied to the small intestine. The promotion function has a promoting effect. The results suggest that Qiongyu ointment has a certain laxative effect on dry heat or dryness and constipation.