Na~+-K~+-ATP酶和Ca~(2+)-Mg~(2+)-ATP酶广泛存在于机体内多种细胞的细胞膜上,其中红细胞因其标本易于采集,准确性高,代表性强,可以作为研究其它多种组织细胞膜Na~+-K~+-ATP酶、Ca~(2+)-Mg~(2+)-ATP酶的生化代表,因而被广泛应用。近年来的研究发现,糖尿病患者红细胞膜Na~+-K~+-ATP酶、Ca~(2+)-Mg~(2+)-ATP酶活性发生变化,且这一变化可能在其慢性并发症的形成中起一定作用。 Na ~ + -K ~ + -ATPase and Ca ~ (2 +) - Mg ~ (2 +) - ATPase are widely found in the cell membrane of many kinds of cells in the body, of which erythrocytes are easy to collect because of their samples, , Which can be widely used as a biochemical representative of Na ~ + -K ~ + -ATPase and Ca ~ (2 +) - Mg ~ (2 +) - ATPase in other cell membranes. In recent years, the study found that diabetic patients with erythrocyte membrane Na ~ + -K ~ + -ATPase, Ca ~ (2 +) - Mg ~ (2 +) - ATPase activity changes, and this change may be in its chronic complications The formation of disease play a role.