本文报告一例18岁女性(体重49kg),因发热、颈部两处溃疡、口腔阿弗他及腹泻而就诊.一年来患者出现乏力,慢性腹泻,时为便血,并有里急后重.入院前8天左耳及耳下出现皮损,很快扩大并坏死,直径达4cm,此后左颈后部亦出现类似皮损一处,诊断为坏疽性脓皮病(PG).患者全身情况差,体检尚发现肛周有直径约为15mm的表浅性溃疡. This article reports an 18-year-old female who weighed 49kg and was diagnosed with fever, two ulcers at the neck, oral altavir and diarrhea. One year she developed fatigue, chronic diarrhea, blood in the stool, and tenesmus. Left and ear lesions appear, and soon expanded and necrosis, the diameter of 4cm, then there is a similar lesion in the left and right posterior part of a diagnosis of pyoderma gangrenosum (PG) .The patient’s general condition is poor, physical examination is still Found perianal diameter of about 15mm superficial ulcers.