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目的探讨厦门市慢性阻塞性肺疾病(COPD)死亡率的影响因素。方法研究对象为2002—2014年厦门市50岁以上居民,死亡数据导出至Excel 2007进行整理分析、制表及画图,用SAS 9.0软件进行非条件logistic回归分析。结果 2002—2014年厦门市50岁以上户籍人口COPD年均死亡率为51.89/10万,城市和农村居民年均死亡率男性均高于女性(P<0.05)。单因素非条件logistic回归分析结果显示,性别、城乡和年龄3个变量差异均有统计学意义(均P<0.01);多因素非条件logistic回归(逐步法)分析结果显示,性别为男性、年龄每增加5岁为COPD死亡率升高的危险因素,生活在城市为保护因素。男性COPD死亡率是女性的2.078倍(OR=2.078,P<0.01);与城市居民相比,农村居民COPD死亡率更高(OR=0.716,P<0.01);年龄每增加5岁,死于COPD的危险性增加(OR=2.328,P<0.01)。结论 COPD已成为厦门市严重的公共卫生问题,其死亡与多种因素相关,应采取综合性的预防控制措施。
Objective To investigate the influencing factors of mortality in chronic obstructive pulmonary disease (COPD) in Xiamen. METHODS: The subjects of the study were residents over the age of 50 from 2002 to 2014 in Xiamen City. The death data were exported to Excel 2007 for analysis, tabulation and drawing. SAS 8.0 software was used to conduct unconditional logistic regression analysis. Results The annual average COPD death rate of urban residents aged 50 years and above from 2002 to 2014 was 51.89 / 100,000. The average annual death rate of urban residents and rural residents was higher than that of women (P <0.05). The univariate non-conditional logistic regression analysis showed that there were significant differences in gender, urban-rural and age-related variables (all P <0.01). The results of multivariate non-conditional logistic regression (stepwise analysis) Each additional 5 years of age is a risk factor for increased COPD mortality and life in the city is a protective factor. Compared with urban residents, the death rate of COPD in rural residents was 2.078 times that of female residents (OR = 2.078, P <0.01). Mortality rate of COPD in rural residents was higher (OR = 0.716, P <0.01) The risk of COPD increased (OR = 2.328, P <0.01). Conclusion COPD has become a serious public health problem in Xiamen City, and its death is related to many factors. Comprehensive preventive and control measures should be taken.