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硝苯啶(nifedipine)为钙通道阻滞剂之一。近年来,随着研究的深入,其临床应用进展较快。笔者试用硝苯啶治疗顽固性呃逆2例效果显著,现报道如下。 例1 男,72yr。因不规则发热1mo,巩膜黄染2wk以胆系感染入院。给予抗感染、利胆等治疗,至d3出现频繁呃逆,经机械性刺激(兴奋迷走神经),药物穴位封闭,口服山莨菪碱、甲氧氯普胺、氟哌啶醇等治疗3d无效,改用硝苯啶10mg舌下含用,tid。用药1次呃逆次数即减少,1d后呃逆停
Nifedipine is one of the calcium channel blockers. In recent years, with the deepening of research, its clinical application has progressed rapidly. The author trial of nifedipine treatment of refractory hiccups two cases of significant results are reported below. Example 1 male, 72yr. Due to irregular fever 1mo, scleral yellow dye 2wk admitted to the gall bladder infection. Given anti-infection, gallbladder and other treatment, to frequent d3 appear hiccup, mechanical stimulation (excitement of the vagus nerve), drug points closed, oral anisodamine, metoclopramide, haloperidol treatment of 3d invalid use Nifedipine 10mg sublingual use, tid. Hiccups times a medication that is reduced, after 1d hiccups stop