端粒是真核细胞染色体末端的一个特殊结构 ,由一段具有特定重复序列的ＤＮＡ和端粒结合蛋白组成 ,是维持染色体结构稳定的重要因素。正常细胞随着细胞分裂活动的进行 ,端粒ＤＮＡ逐渐缩短 ,当缩短到一定程度时 ,染色体结构被破坏 ,细胞进入衰老期并以死亡而告终。但肿瘤细胞似 Telomere is a special structure at the end of chromosome of eukaryotes. It consists of a DNA with specific repeat sequence and telomere binding protein, which is an important factor to maintain the structural stability of chromosome. Normal cells as cell division activity, telomere DNA gradually shortened, when shortened to a certain extent, the chromosomal structure is destroyed, the cells into the senescence and died. But tumor cells like