鱼藤素是鱼藤酮类化合物,存在于非洲植物栓皮豆Mundulea sericea中,对小鼠皮肤癌和大鼠乳腺癌模型有明显的化学防护作用。作者用 HPLC联合 ES-MS(电子喷雾质谱分析)检测了在几种载体中的鱼藤素降解产物和稳定性。色谱柱选用 Novapak C_(18)柱(3.9×150mm),流动相为乙腈-水(55:45,v/v),UV检测波长 270nm,流速1mL/min,鱼藤素的 Deguelin is a rotenone compound that is found in the African plant Mundulea sericea and has significant chemical protection against mouse skin and rat breast cancer models. The authors used HPLC and ES-MS (Electrospray Mass Spectrometry) to detect deguelin degradation products and stability in several carriers. The column was Novapak C 18 column (3.9×150mm), the mobile phase was acetonitrile-water (55:45, v/v), the UV detection wavelength was 270nm, the flow rate was 1mL/min, and the deguelin was