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近年来微电极方法,电子显微镜技术及希氏束电图的临床应用,使心律失常及抗心律失常药物的研究达到了细胞水平。本文从电生理学角度评述抗心律失常药物的药理作用。心肌细胞的动作电位及其电生理特性心肌细胞动作电位及其离子转运静息的心肌细胞跨膜有内负外正的静息
In recent years, the clinical application of microelectrode method, electron microscopy and His bundle electrogram has made the research of arrhythmia and antiarrhythmic drugs reach the cellular level. This article reviews the pharmacological effects of antiarrhythmic drugs from electrophysiology. Action potentials of cardiomyocytes and their electrophysiological properties Cardiomyocytes action potentials and their transport of ions Resting cardiomyocytes transmembrane with negative and positive rest