[答]耳毒性药物,一般是指选择性损伤第八对脑神经(位听神经)的药物。表现为眩晕、平衡失调和耳鸣、耳聋等内耳症状。常见耳毒性药物有:氨基甙类抗菌素、襻性利尿剂(利尿酸、速尿等)、水杨酸类、奎宁类以及非固醇类消炎镇痛剂(消炎痛、布洛芬等)等等。据国外统计,药物性耳聋的发生率约为0.3%,其中以氨基甙类抗菌素最高,为13‰;其次是阿司匹林,为11‰;第三是利尿酸 [Answer] ototoxic drugs, generally refers to the selective damage to the eighth pair of cranial nerves (bit auditory nerve) drugs. Performance for dizziness, balance disorders and tinnitus, deafness and other symptoms of the inner ear. Common ototoxic drugs are: aminoglycoside antibiotics, carbuncle diuretics (uric acid, furosemide, etc.), salicylic acid, quinine and non-steroidal anti-inflammatory analgesic agents (indomethacin, ibuprofen, etc.) and many more. According to foreign statistics, the incidence of drug-induced deafness is about 0.3%, of which aminoglycoside antibiotics highest, 13 ‰; followed by aspirin, 11 ‰; the third is the uric acid