先兆子痫是孕产妇、新生儿发病和死亡的重要原因之一。原发性高血压、糖尿病、肥胖等诱发先兆子痫的疾病患病率越来越高。许多证据表明,在先兆子痫发生之前已出现微循环异常。该研究假设检测毛细血管稀疏程度有助于预测先兆子痫。方法:连续入选322名女性白人,其中发生先兆子痫16例。应用公认的检查手段按照预先规定的时间对研究对象连续5次测量皮肤毛细血管密度。结果:妊娠20～24周的孕妇,以每视野2个毛细血管为指标,毛细血管密度预测 Pre-eclampsia is one of the important causes of maternal morbidity and mortality in newborns. The prevalence of diseases causing essential eclampsia such as essential hypertension, diabetes and obesity is getting higher and higher. Much evidence suggests that microcirculation abnormalities have occurred before pre-eclampsia. The study hypothesized that detecting the degree of capillary sparseness may help predict preeclampsia. Methods: A total of 322 female white subjects were enrolled, of whom 16 had preeclampsia. The accepted method of examination was used to measure the density of the capillaries of the subject five times in a row for a predetermined period of time. Results: Pregnant women of 20-24 weeks of pregnancy, with two capillaries per field as an indicator, capillary density