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目的 :探讨术前放射介入动脉灌注化疗对进展期胃癌的治疗效果。方法 :对 30例进展期胃癌患者采用 Seldinger法行术前放射介入动脉灌注化疗 ,一次大剂量将抗癌药物注入肿瘤供血动脉 ,观察临床症状、血清 CEA、大体病理和病理切片的变化情况 ,与未行化疗的对照组进行比较。结果 :术前动脉灌注化疗组化疗后临床症状明显改善 ,血清 CEA降低 ,肿瘤坏死、缩小 ,病理检查见肿瘤细胞坏死、炎细胞浸润、纤维组织增生。结论 :术前动脉灌注化疗毒副作用小 ,可改善临床症状 ,缩小病灶 ,提高手术切除率及手术治疗效果
Objective: To investigate the effect of preoperative radiofrequency catheterization chemotherapy on advanced gastric cancer. Methods: Thirty patients with advanced gastric cancer undergoing preoperative radiological interventional chemotherapy with Seldinger method were infused with a large dose of anticancer drug into the tumor feeding artery to observe the changes of clinical symptoms, serum CEA, gross pathology and pathological sections, and The control group without chemotherapy was compared. Results: Preoperative arterial infusion chemotherapy significantly improved the clinical symptoms, serum CEA decreased tumor necrosis, reduced, the pathological examination showed tumor cell necrosis, inflammatory cell infiltration, fibrous tissue hyperplasia. Conclusion: Preoperative arterial infusion of chemotherapy side effects, can improve clinical symptoms, reduce the lesion and improve the surgical resection rate and surgical treatment effect