高渗性高血糖性昏迷(以下简称高渗性昏迷)是糖尿病急性并发症之一。自1957年Sament 等和 de Graeff 等作了首例报告之后,对本病的认识逐渐加深,发现此并发症并非罕见。它起病隐匿、症状凶险而又易为基础疾病及合并症掩盖、死亡率高,因此受到临床医师的重视。本文报告1975年以来收治的6例高渗性昏迷,结合近年国内文献报告之14例就本症的诊断问题进行初步分析和讨论。 Hyperosmolar hyperglycemic coma (hereinafter referred to as hypertonic coma) is one of the acute complications of diabetes. Since the first report of Sament et al. And de Graeff et al. In 1957, the understanding of this disease has deepened and found that this complication is not uncommon. It occult onset, the symptoms are dangerous and easy to cover the underlying diseases and complications, high mortality, it has been clinician’s attention. This article reports 6 cases of hypertonic coma admitted since 1975, combined with the recent domestic literature report of 14 cases of the diagnosis of the disease for a preliminary analysis and discussion.