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作者鉴于在糖尿病时,临床常疑有抗感染功能的减退,但尚无病理生理学的阐明。故对97例不同类型、不同病期的糖尿病,研究了白细胞防御感染功能。资料和方法对糖尿病患者白细胞的趋化性、吞噬作用、杀菌力及碘化试验等进行测定。趋化性的测定,系用放在前臂皮肤上的塑料小室,室内充满自家血清,观察8小时内被动员入小室的白细胞数。吞噬作用的测定,系用胶乳颗粒同粒细胞孵育5～10分钟后,测定其吞噬活性指数,即有吞噬作用的粒细胞的百分率与其吞噬程度(0～4级)的乘积。杀菌力试验,系用改良的Cline试验,即将大肠杆菌同患者粒细胞进行孵育后,加入~3氢标记的胸腺嘧啶,观察
In view of diabetes, the clinical suspicion of anti-infective function decline, but no pathophysiology of clarification. Therefore, 97 cases of different types and stages of diabetes mellitus, white blood cell defense infection function. Materials and Methods The leukocyte chemotaxis, phagocytosis, bactericidal and iodine test of diabetic patients were determined. Chemotaxis determination, Department of plastic skin on the forearm with the chamber filled with their own homes, observe the number of leukocytes mobilized into the chamber within 8 hours. Determination of phagocytosis, Department of latex particles with granulocytes incubated with 5 to 10 minutes after the determination of phagocytic activity index, the percentage of phagocytic granulocytes and its phagocytosis degree (0 to 4) product. Bactericidal test, Department of improved Cline test, about to E. coli with the patient after incubation of granulocytes, add ~ 3 hydrogen-labeled thymidine, observed