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用无特殊致病菌大鼠制作失血性休克动物模型,对失血性休克后肠道细菌易位与血中内毒素水平的变化进行了动态观察。发现失血性休克后所有动物均发生了肠道细菌易位。在复苏后5小时,肠道细菌易位达高峰,85％的标本细菌培养阳性,而后逐渐减少。血中内毒素水平也有类似改变。提示失血性休克后肠道细菌易位与内毒素血症是一个普遍存在的过程。
Animal models of hemorrhagic shock were made in rats without special pathogens, and dynamic changes of intestinal bacterial translocation and blood endotoxin levels after hemorrhagic shock were observed. Intestinal bacterial translocation occurred in all animals after hemorrhagic shock was found. Five hours after resuscitation, intestinal bacterial translocation peaked, and 85% of specimens were positive for bacterial culture and then gradually decreased. Blood endotoxin levels also have similar changes. Suggest that intestinal bacterial translocation and endotoxemia after hemorrhagic shock are a ubiquitous process.