应用电子计算机实时分析了豚鼠心室肌动作电位的零相除极过程。零相除极的膜电位变化曲线类似“S”形,除极速率变化包括加速和减速两个过程。V_(max)恒定出现在膜电位除极至-21±SD 11mV时,相当于零相除极的60.1±SD 8.1％。河豚毒素(te-trodotoxin,TTX)显著降低零相除极的幅度和速率,除极速率减慢过程类似于一反向抛物线,与TTX呈剂量依赖性,主要变化部分位于V_(max)附近的加速期中。 The application of computer real-time analysis of guinea pig ventricular action potential zero phase depolarization process. Zero-phase depolarization membrane potential curve similar to the “S” shape, including the rate of change in speed, including acceleration and deceleration process. V_ (max) is constant at 60.1 ± SD 8.1% of the zero phase depolariza- tion when the membrane potential is depolarized to -21 ± SD 11 mV. Tetrodotoxin (TTX) significantly reduced the magnitude and rate of zero-phase depolarization. The depolarization rate slowed down in a similar manner to a reverse parabola, which was in a dose-dependent manner with TTX, and the major changes were located near V max In the acceleration period.