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RNA 对实验性四氯化碳引起的肝损害有保护作用,可改善慢性肝炎(CH)和肝硬化(HC)病人症状和肝功能,并通过促进肝细胞合成 DNA 和蛋白质改善血清蛋白比例。实验证明 RNA 有明显抗肝纤维化的作用,现对 RNA 抗肝纤维化的临床与病理进行观察,结果如下。资料与方法一、病例选择与分组以口服肌苷、维生素 B、C,静脉滴注复方氨基酸500ml 2～3次/周为基础治疗。随机分为二组,RNA 治疗组82例(江苏省如皋生化制药厂产品,为正常猪肝中提取的 RNA 冻干粉针剂),6mg 肌注每日1次,疗程3个月。辅酶 Q_(10)治疗组80例,
RNA protects against experimental carbon tetrachloride-induced liver damage, improves symptoms and liver function in patients with chronic hepatitis (CH) and cirrhosis (HC), and improves serum protein by promoting the synthesis of DNA and protein by hepatocytes. Experiments show that RNA has obvious anti-liver fibrosis, RNA anti-liver fibrosis now observe the clinical and pathological findings are as follows. Materials and methods A case selection and grouping In oral inosine, vitamin B, C, intravenous infusion of compound amino acids 500ml 2 to 3 times / week as the basis for treatment. Randomly divided into two groups, RNA treatment group of 82 cases (Jiangsu Rugao biochemical pharmaceutical products, extracted from normal pig liver RNA freeze-dried powder), 6mg intramuscular injection once daily for 3 months. Coenzyme Q_ (10) treatment group of 80 cases,