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目的探讨应用弥可保合用灯盏花素治疗老年糖尿病周围神经病变(DPN)的临床疗效。方法91例老年糖尿病周围神经病变患者随机分为治疗组和对照组2组,治疗组46例应用弥可保、灯盏花素静脉滴注,对照组45例单独静脉滴注弥可保。结果发现弥可保合用灯盏花素可以更有效地减轻患者的肢体麻木、疼痛、发凉等临床症状,胰岛素敏感性增加,植物神经功能障碍也有所改善。应用弥可保合用灯盏花素治疗老年糖尿病周围神经病变的治疗组与单纯应用弥可保的对照组疗效比较,前者有效率明显高于后者,两组间差异有统计学意义。在治疗过程中,没有明显副作用及不良反应,这种联合应用是安全有效的。结论弥可保联合应用灯盏花素是一种比较理想的中西医结合治疗老年糖尿病周围神经病变的治疗方法。
Objective To investigate the clinical effect of using erigeron breviscapine in the treatment of senile diabetic peripheral neuropathy (DPN). Methods Ninety-one elderly patients with diabetic peripheral neuropathy were randomly divided into two groups: treatment group and control group. In the treatment group, 46 patients were treated with methycoprop and breviscapine intravenously, and 45 in the control group were given intravenous methycobal alone. The results showed that Mi Kebao Breviscapine can be more effective in alleviating the patient’s numbness, pain, cold and other clinical symptoms, increased insulin sensitivity, autonomic dysfunction has also been improved. The application of miconazole compatibility Breviscapine treatment of elderly diabetic peripheral neuropathy treatment group compared with the simple application of cancobal control group, the former effective rate was significantly higher than the latter, the difference between the two groups was statistically significant. In the course of treatment, no obvious side effects and adverse reactions, this joint application is safe and effective. Conclusion Miraculous combination of Breviscapine is an ideal treatment for senile diabetic peripheral neuropathy with integrated traditional Chinese and Western medicine.