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木文作者认为脾切除是延长慢性粒细胞性白血病生存期的方法。本文报告包括急性变52例在内的CML 110例,对患者的年龄,初诊时白细胞数和急性变的关系,脾切除病例的组织学检查和适应症等进行讨论。生存者44例,死亡63例(内52例急性变),情况不明者3例。诊断时白细胞数不满5万者25例(以集体体检,早期发现为主);5~10万者21例;10~20万者23例;超过20万的27例。诊断时白细胞数和到急性变的时间:白细胞1~5万者90个月;5~10万者50个月左右。从1万增加至15万要经过23个月。年龄和急性变的关系:不满29岁的时间稍短,但无显著差别。关于脾切除的病例:第1例从诊断到急性变30个月,在此期间作牌切除和残留胃
Wood authors believe that splenectomy is to extend the survival of chronic myelogenous leukemia method. This article reports 110 cases of CML including 52 cases of acute change. The age of patients, the number of leucocytes and acute changes at the initial diagnosis, the histological examination and indications of splenectomy were discussed. 44 survivors, 63 deaths (52 cases of acute change), unknown cases in 3 cases. On diagnosis, there were 25 cases with less than 50,000 white blood cells (mainly in collective examination and early detection); 21 cases with 5-10,000 people; 23 cases with 10-200,000 people and 27 cases with more than 200,000. The number of white blood cells at diagnosis and the time of acute change: white blood cells 1 to 5 million for 90 months; 5 to 10 million for about 50 months. From 10,000 to 150,000 to go through 23 months. Relationship between age and acute change: less than 29 years of age slightly shorter, but no significant difference. On the splenectomy cases: the first case from diagnosis to acute change 30 months, during which a card resection and residual stomach