宫颈癌经多疗程化疗后部分患者产生耐药 ,导致化疗失败 ,此时采用放射治疗时 ,患者对放疗反应较差 ,对放疗后复发的患者采用化疗时 ,往往对化疗不敏感 ,这已成为近十年来晚期宫颈癌生存率无明显提高的主要原因。本研究从细胞凋亡的角度 ,以人宫颈癌 He La细胞及其耐药细胞 He L Cervical cancer is refractory to chemotherapy after some courses of chemotherapy, resulting in poor chemotherapy response. In this case, radiotherapy is used to treat patients with poor response to radiotherapy. When chemotherapy is used in patients who relapse after radiotherapy, they are often not sensitive to chemotherapy. This has become The main reason for no significant improvement in the survival rate of advanced cervical cancer over the past decade. This study from the perspective of apoptosis, human cervical cancer He La cells and drug-resistant cells He L