乳腺癌是来源于乳腺终末导管小叶单元上皮的恶性肿瘤,多发生于中老年女性,是目前威胁女性健康常见的疾病之一。其发病率在过去的几十年中逐年增高,已跃居女性恶性肿瘤的首位。近年来的研究发现,Twist作为一种肿瘤相关基因,其在乳腺癌的发生、发展以及诊断、治疗和预后中起着重要作用。 Breast cancer is a malignant tumor derived from epithelial cells of terminal ductal lobes of mammary glands. It occurs in middle-aged and elderly women and is one of the common diseases threatening women’s health. Its incidence has increased year by year in the past few decades, has leapt to the top of female malignant tumors. Recent studies have shown that Twist, as a tumor-associated gene, plays an important role in the occurrence, development, diagnosis, treatment and prognosis of breast cancer.