随着医学超声影像学的新技术层出不穷,从彩色多普勒超声到超声造影到超声微泡携基因靶向破坏定位释放技术,极大的拓展了超声的临床应用范围,尤其是超声微泡介导基因在肿瘤基因治疗领域中的应用日益广泛,可以促进目的基因在肿瘤细胞中的转染,具有更高的靶向性和安全性,现就其超声微泡携基因靶向治疗妇科肿瘤的研究进展作一综述。 With the advent of new technologies in medical ultrasound imaging, from color Doppler ultrasound to ultrasound contrast to ultrasound microbubbles targeted release of targeted release of genes, which greatly expanded the clinical application of ultrasound, especially ultrasound microbubbles mediated Guiding gene in the field of cancer gene therapy is widely used, can promote the target gene transfection in tumor cells, with higher targeting and safety, is now on its ultrasound microbubbles carry gene targeting treatment of gynecological tumors The research progress is reviewed.