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短肠综合征病人常发生营养不良和水、盐的丢失,大多数小肠短于80~100cm 的病人需长期静脉补充营养。但肠功能不全的严重程度不仅取决于残留小肠的长度,其他一些因素如切除小肠的部位、现存的粘膜病变和所产生的适应代偿程度均可影响其结局。再者,手术时对肠道长度的测量亦受技术原因和由于肠道纵形肌收缩而产生误差。本文对17例作过不同程度肠切除的病人用液态试餐进行能量吸收试验研究,这种衡量吸收能力的机能性检测方法可克服上述困难。方法:研究对象分为三组。第一组:5例回肠造口术病人,其末端回肠切除少于60cm,所保留的肠道无病变,无需静脉补充营养;第二组:7例短肠综合征病人,能维持稳定和满意的营养状态,而不依赖长期静脉补充营养。中位数小肠长度为110cm(范围60~140cm);第三组:5例短肠综合征病人,需长期依赖静脉补充营养,中位数小肠长度为50cm(范围20~100cm)。所有对象在研究前48小时停用一切抗腹泻药物。空腹一夜后,在10~15分钟内摄入标记有5μCi 三氢聚乙
Patients with short bowel syndrome often malnutrition and water and salt loss, most of the small intestine shorter than 80 ~ 100cm patients need long-term intravenous nutritional supplements. However, the severity of intestinal insufficiency depends not only on the length of the remaining small intestine, but also on other outcomes such as the site of excision of the small intestine, existing mucosal lesions, and the degree of accommodation due to adaptation. Furthermore, the measurement of the length of the intestine during surgery is also erroneous due to technical reasons and due to the contraction of the intestinal longitudinal muscles. In this paper, 17 cases of patients with different degrees of intestinal resection with liquid test meal energy absorption test study, this measure of absorptive capacity of the functional test to overcome these difficulties. Methods: The subjects were divided into three groups. The first group: 5 cases of ileostomy patients, the terminal ileum resection less than 60cm, the reserved bowel disease-free, without intravenous nutritional supplements; Group II: 7 cases of short bowel syndrome patients, to maintain stability and satisfaction Of the nutritional status, without relying on long-term intravenous nutritional supplements. The median length of the small intestine is 110 cm (range, 60-140 cm). The third group: 5 patients with short bowel syndrome, long-term dependence on intravenous nutritional supplements, the median length of the small intestine is 50cm (range 20 ~ 100cm). All subjects discontinued any anti-diarrhea medication 48 hours prior to study. After an overnight fasting, in 10 to 15 minutes of intake labeled with 5μCi trimethoprim