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用谱估计方法对10名健康被试者平静呼吸时的呼吸气体流率、食管压力信号进行了分析,求出自基频至3倍频的肺阻力(R_L)及动态顺应性(C_(dyn))。结果如下:①C_(dyn)在10名被试者均表观为随呼吸信号谐波频率的增高而降低。在基频,2倍频和3倍频下,C_(dyn)的均值依次为,4.3±1.3、2.4±0.6及2.3±0.5(kPa~(-1)·L)②R_L在6名被试者表现为随呼吸信号谐波频率的增高而降低;2名被试者表现为随呼吸信号谐波频率的增高而增高。在基频、2倍频及3倍频下,R_L的均值依次为,0.14±0.05、0.13±0.05及0.12±0.05(kPa·L~(-1)·s)用谱估计方法分析C_(dyn)的频率依赖特性对小气道病变的早期诊断可能有一定意义。
Respiratory gas flow and esophageal pressure signals of 10 healthy subjects were measured by the method of spectral estimation. The lung resistance (R_L) and dynamic compliance (C_ (dyn) )). The results are as follows: ①C dyn was apparently decreased with increasing harmonic frequency of respiratory signal in 10 subjects. The average values of C dyn at the fundamental frequency, second harmonic frequency and third harmonic frequency were 4.3 ± 1.3, 2.4 ± 0.6 and 2.3 ± 0.5 (kPa -1) L) Manifested as the respiratory signal harmonic frequency decreases; two subjects showed as the respiratory signal harmonic frequency increases. At the fundamental frequency, second harmonic frequency and third harmonic frequency, the average R_L values were 0.14 ± 0.05, 0.13 ± 0.05 and 0.12 ± 0.05 (kPa · L -1 · s) ) Frequency-dependent characteristics of small airway lesions may have some significance in the early diagnosis.