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实验方法 大耳白家兔,性别不拘,计16只,体重2.25±0.5Kg。用尿酯1g/kg静脉麻醉后,行一侧颈总动脉、股动脉静脉插管术以及肾动脉分离术。颈总动脉插管接血压换能器测血压,股动脉插管接蠕动泵及贮血瓶放血,用蠕动泵控制放血速度。当血压稳定在5.3kPa左右时为代偿期。当血压开始低于5.3kPa时,记录总放血量,反向开动蠕动泵,使血回输至血压升为5.3kPa左右停止,此时为失代偿期。当回输血液达总放血量的20％时,为晚期失代偿期开始。将血改从股静脉输入(1ml/分钟),同时经耳静脉滴入药物或生理盐
Experimental methods White-eared rabbits were randomly divided into sex numbers and counted as 16 and weighing 2.25±0.5 Kg. After intravenous anesthesia with urine ester 1g/kg, one side common carotid artery, femoral vein catheterization, and renal artery dissection were performed. The common carotid artery was cannulated and connected to a blood pressure transducer to measure blood pressure. The femoral artery was cannulated and connected to a peristaltic pump and a blood-storing bottle to exsanguine. A peristaltic pump was used to control the bloodletting speed. When the blood pressure stabilizes around 5.3kPa, it is the compensatory period. When the blood pressure starts to fall below 5.3 kPa, the total blood loss is recorded, and the peristaltic pump is turned on in the opposite direction so that the blood is returned to about 5.3 kPa as the blood pressure rises. This is the decompensation period. When the blood is returned to 20% of the total blood loss, the late decompensation period begins. The blood was changed from the femoral vein (1 ml/min), while the drug or physiological salt was instilled through the ear vein.