本文介绍一种结构简单、易于放大的新型好氧中空纤维生物反应器。它是将一束混合的亲水性中空纤维膜和疏水性中空纤维膜插入玻璃管反应器身,并在反应器身的每个末端用碳化硅胶分别密封这两种膜。液体培养基在亲水性膜腔内流动,气体培养基在疏水性膜腔内流动,微生物细胞在壳内培养。该反应器的侧壁设有一接种口,气、液培养基流向相反。和传统的中空纤维生物反应器相比,这种新型生物反应器提高了气体传送能 This paper introduces a new type of aerobic hollow fiber bioreactor with simple structure and easy enlargement. It is a mixture of hydrophilic hollow fiber membrane and hydrophobic hollow fiber membrane inserted into the glass reactor body, and at each end of the reactor body were sealed with silica gel respectively. The liquid medium flows in the hydrophilic membrane cavity, the gas medium flows in the hydrophobic membrane cavity, and the microbial cells are cultured in the shell. The side wall of the reactor is provided with an inoculation port, and the gas and liquid culture medium flow in the opposite direction. Compared with the traditional hollow fiber bioreactor, this new type of bioreactor increases the gas delivery