论文部分内容阅读
本实验证实了祝寿河首先提出的坏死性小肠结肠炎的微循环障碍发病学说。在实验中,把内毒素注入家兔肠壁内24小时后,静脉注入内毒素,可复制成与人类坏死性小肠结肠炎病理改变相近似的节段性肠淤血、水肿、出血以致坏死的模型。将内毒素改成去甲肾上腺素,也同样可激发上述节段性改变。若先给酚妥拉明再给去甲肾上腺素,则可阻止其出现。提示:(1)坏死性小肠结肠炎与内毒素局部型施瓦茨曼反应有关。(2)内毒素所致的小血管α-受体反应性增加与坏死性小肠结肠炎的发病有关。
This experiment confirms the first theory proposed by Zhu Shouhe necrotizing enterocolitis pathogenesis of microcirculation. In the experiment, endotoxin was infused into the intestinal wall of rabbits 24 hours after intravenous injection of endotoxin, can be replicated into the pathological changes similar to human necrotizing enterocolitis segmental intestinal congestion, edema, bleeding necrosis model . The endotoxin into norepinephrine, but also can stimulate the above-mentioned segmental changes. If given to phentolamine give norepinephrine, you can prevent it from appearing. Tip: (1) necrotizing enterocolitis and endotoxin local Schwartz reaction. (2) The increased endotoxin-induced small-vessel α-receptor reactivity is associated with the pathogenesis of necrotizing enterocolitis.