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采用肠穿孔和腹腔注入大肠杆菌制备幼猪腹膜炎致感染性休克模型结果:动物全死于败血症和感染性休克,平均生存时间354min;心输出量、心脏指数等指标在感染性休克的发生和发展过程中变化显著(P<0.05)。说明在腹膜炎和败血症期出现短暂的高血液动力学表现提示感染性休克早期。
The model of septic shock induced by intestinal perforation and peritoneal injection of E.coli in peritonitis of young pigs was established. The animals died of sepsis and septic shock with an average survival time of 354 min. The cardiac output, cardiac index and other indicators of septic shock The process changes significantly (P <0.05). This shows that transient hyperkinetic performance during peritonitis and sepsis suggests early septic shock.