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报道了成功地亚克隆Ｚｆｈａｇ的锌指结构和同结构域基因，并将其在细菌体内表达成麦芽糖结合蛋白的融合蛋白的方法和结果，使用这些表达蛋白进行了蛋白－ＤＮＡ相互作用的研究。结果表明：ＭＢＰ－ＺＤ１和ＭＢＰ－ＺＤ２蛋白能与糖蛋白激素的α亚基基因、鼠生长激素（γ－ＧＨ）基因和促甲状腺激素β亚基（ＴＳＨ－β）基因的甲状腺激素反应成分（ＴＲＥ）结合，而不能结合含有天然ＴＲＥ的ＭＨＣ和Ｆ２Ｈ基因，及含有合成ＴＲＥ的ＤＲ４和ＰＡＬ寡核苷酸。
The methods and results of successfully subcloning Zfhag zinc finger and syndiotactic genes and expressing them in the bacterium as fusion proteins of maltose-binding proteins were reported. Protein-DNA interactions were studied using these expressed proteins. The results showed that the MBP-ZD1 and MBP-ZD2 proteins could interact with the thyroid hormone response component of the α-subunit of glycoprotein, the gene of murine growth hormone (γ-GH) and the TSH-β TRE), but not MHR and F2H containing natural TRE, and DR4 and PAL oligonucleotides containing synthetic TRE.