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应用酶联亲和组化法及网格点计数方法，对３０例乳腺癌、３８例纤维腺瘤、３９例小叶增生及２３例非癌组织的雌激素受体（ＥＲ）和孕酮受体（ＰＲ）及细胞密度进行检测和分析。结果：①纤维腺瘤、小叶增生及非癌组织中ＥＲ、ＰＲ的阳性率均分别低于癌中的表达（Ｐ＜０．０５），纤维腺瘤与小叶增生之间受体表达无显著性差异（Ｐ＞０．０５）。②各组病变中细胞密度的高低与受体阳性表达有关（Ｐ＜０．０５）。提示：乳腺良性病变中ＥＲ、ＰＲ阳性率的不同，为临床内分泌治疗提供理论依据。
Using enzyme-linked affinity immunohistochemistry method and grid point counting method, estrogen receptor (ER) and progesterone receptors in 30 cases of breast cancer, 38 cases of fibroadenoma, 39 cases of lobular hyperplasia, and 23 cases of non-cancer tissues (PR) and cell density were tested and analyzed. Results: 1The positive rates of ER and PR in fibroadenoma, lobular hyperplasia and non-cancer tissues were all lower than those in cancer (P<0.05). There was no significant difference in receptor expression between fibroadenoma and lobular hyperplasia. Difference (P>0.05). 2 The density of cells in each group was related to the positive expression of receptors (P<0.05). Tip: The difference in positive rates of ER and PR in benign breast lesions provides a theoretical basis for clinical endocrine therapy.