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本文以１６例椎—基底动脉闭塞的病理、临床资料为基础，探讨了病理与临床特点。椎—基底动脉闭塞以基底动脉中段多见，栓塞多于血栓。病变主要波及桥脑、枕叶、颞叶及丘脑。约半数病人并存基底节区梗塞。本组病理资料提示脑动脉粥样硬化是发病的重要条件，也是本病常见于老年人的病理基础。起病时常见的症状有眩晕、呕吐、偏侧或双侧肢体瘫痪、言语不清及突然意识不清等。病变过程中比较有特征性的体征有眼肌麻痹、眼球震颤、构音障碍、双软腭提举力差、双侧肢体瘫痪、双侧病理反射阳性。ＣＴ对本病诊断的帮助不大。
Based on the pathological and clinical data of 16 cases of vertebrobasilar occlusion, the pathological and clinical features were discussed. Vertebrobasilar occlusion is more common in the middle basilar artery, embolism more than thrombus. Lesions mainly affect the pons, occipital lobe, temporal lobe and thalamus. About half of patients with basal infarction. This group of pathological data suggest that cerebral atherosclerosis is an important condition for the disease, but also the pathology common in the elderly pathological basis. Common symptoms of onset are dizziness, vomiting, paralysis of both lateral and bilateral limbs, vague language and sudden unconsciousness. Pathological changes in the more characteristic signs of ophthalmoplegia, nystagmus, dysarthria, double soft palate lift poor, paralyzed bilateral limbs, bilateral pathological reflex positive. CT diagnosis of the disease is not helpful.