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用Ames和小鼠骨髓嗜多染红细胞(PCE)微核试验对三种类型国产柴油机废气颗粒物进行了致突变性检测。Ames试验结果表明,6120型柴油机废气颗粒物剂量在500μg/皿以上,加与不加S9条件下TA98和TA100的致突变性均呈阳性,S-195型柴油机废气颗粒物在剂量1000μg/皿,不加S9条件下TA98和TA100呈阳性;而4115型柴油机废气颗粒物未显阳性。小鼠骨髓嗜多染红细胞做核试验呈阴性结果。研究结果表明,某些国产柴油机的废气颗粒物具有明显的诱变性且不同类型的柴油机其废气颗粒物的致突变性存在明显差异。
Ames and mouse bone marrow polychromatic erythrocyte (PCE) micronucleus test of three types of domestic diesel particulate matter emissions were mutagenicity testing. Ames test results show that 6120 diesel particulate matter emissions above 500μg / dish, with and without S9 conditions TA98 and TA100 mutagenicity were positive, S-195 diesel exhaust particulate matter at a dose of 1000μg / dish, without TA9 and TA100 were positive under the conditions of S9; while the exhaust particles of 4115 diesel engine were not positive. Mouse bone marrow polychromatic erythrocytes do nuclear test negative results. The results show that some of the domestic diesel exhaust particulate matter has obvious mutagenicity and different types of diesel engine exhaust particulate matter mutagenicity there are significant differences.