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在大多数直接估计临床诊断超声对健康危害的生物效应实验中,应用医学聚焦换能器是方便且似乎是现实的,但这种方法会带来两个问题: 1.一个聚焦辐射场,由于其最高辐射级仅仅在被声波作用的样品内一个非常小的聚焦体积内,因此可能会掩盖波作用的某些效应。如果用一个强辐射级均匀地辐射在整个样品上,能增加检测生物效应的灵敏度; 2.尽管实验中其它的因素可能会导致模糊的剂量与响应关系,而极其不均匀的声场的应用可能是产生这种模糊关系的首要因素。对于在生物样品中均匀辐射的要求,在目前的指导超声生物效应研究的官
In most biological effects experiments that directly estimate the health hazard of clinically diagnosed ultrasound, it is convenient and seems plausible to apply a medical focusing transducer, but this approach poses two problems: 1. A focused radiation field that, due to Its highest radiation level is only within a very small focused volume in a sample acoustically affected and may therefore mask some of the effects of wave action. Sensitivity to detect biological effects can be increased if a strong radiation level is used to evenly irradiate the entire sample; 2. Although other factors in the experiment may lead to ambiguous dose-response relationships, the application of an extremely inhomogeneous sound field may be The primary factor in creating this fuzzy relationship. For the requirement of uniform radiation in biological samples, the current guide to the study of biological effects of ultrasound