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对28 例尿毒症出血患者进行临床分析,原发病以慢性肾炎最多,值得重视的病因是鱼苦胆中毒和非法堕胎所致急性肾衰。临床常表现为瘀斑、紫癜、鼻衄、牙龈出血等,如内脏或颅内出血及继发 D I C,则预后不佳。观察了:(1) 血小板计数与形态;(2) 出、凝血时间;(3) 血小板功能与抗体;(4) 骨髓涂片;(5) 束臂试验和(6) D I C 筛选试验6 项指标,结合文献讨论了尿毒症出血机理中血小板功能障碍是主要因素,毛细血管损伤等也与出血有关。透析能改善血小板功能和出血情况,肾移植是治疗尿毒症出血的最有效措施。
28 cases of uremic hemorrhage in patients with clinical analysis of the primary disease with the most chronic nephritis, the cause is worthy of attention is fish jaundice poisoning and acute renal failure caused by illegal abortion. Clinical manifestations of ecchymosis, purpura, epistaxis, bleeding gums, such as visceral or intracranial hemorrhage and secondary DIC, the prognosis is poor. Observed: (1) platelet count and morphology; (2) out of clotting time; (3) platelet function and antibodies; (4) bone marrow smear; (5) beam arm test and (6) DIC screening test 6 Item index, combined with the literature discussed the uremic hemorrhage platelet dysfunction in the mechanism is the main factor, such as capillary damage also associated with bleeding. Dialysis can improve platelet function and bleeding, renal transplantation is the most effective treatment of uremic bleeding.